Archive for the ‘Field / Technique’ Category

Details of the weight loss A new study published in the NEJM enrolled 50 overweight or obese patients (BMIs between 27 and 40) in a 10-week 500 calorie diet of Optifast VLCD and low starch vegetables. As might be expected with such a rigorous diet 16 dropped out or did not lose the expected weight […]


There is a belief in the drug community that the war on drugs prevents good research from being done on drug use. While I agree there is a scarcity of research on the potential uses of many abused drugs or how they alter states of consciousness we really do know an amazing amount about what […]


Viberg of the Eriksson lab in Sweden shows in a new paper in Toxicology (full text) that a single exposure to BPA on postnatal day 10 has dose-dependent effects. (Mice sexually mature around p45.) The paper is still in press, so details are sparse, but authors saw changes in spontaneous behavior when exposed to a […]


Just saw Paul Garrity present an interesting story on the function and evolution of TRPA1–a chemical and temperature sensitive cation channel of the transient receptor potential family. He initially discovered TRPA1’s role in thermosensation using an RNAi screening of drosophila larvae on a thermal gradient. As small ectotherms (a term which essentially means cold-blooded), drosophila […]